Remember when I posted about the highly-similar
cyclobutane insertion chemistry coming out of the Cramer group? Well, a new contestant has
just been published in
ACIEE:
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Source: Cramer, ACIEE 2014 |
I jumped down the rabbit-hole of the Supporting Information, and returned with these two "general" procedures - blink, and you'll miss the differences!
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Source: Cramer et. al., ACIEE 2014, February |
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Source: Cramer et. al., ACIEE, 2014, July |
Same catalyst precursor. Same ligand (
well, different enantiomer). Same solvent. Same time. Similar reaction temps and purification conditions. Now, I'm not saying that the Cramer group shouldn't have published this paper, but in the same journal? With essentially the same substrates?
Does anyone else believe that these could have been published together, in a single high-impact paper?